MICR 270, Infection, Immunity and Inflammation, is designed for students from various biological sciences and allied health backgrounds at all levels of post-secondary education and is recommended as a foundation course for students pursuing a career in the health sciences. This course focuses on the biology of the immune system in combating infections caused by common pathogens as well as major global infectious disease threats. The unique features of this course lie in its approach of understanding body’s defense mechanisms in combating microbial, autoimmune, immune mediated diseases and cancer. By the end of the course the student will be able to apply the knowledge gained through this course in various areas of life sciences.
*Note that BHSc program students are required to take one of MICR 270/3.0 or MICR 271/3.0.
Minimum 2nd year (Level 2) standing + 4U Biology recommended and (PHGY 170/3.0) or (BIOL 102/3.0) or (MICR 121/3.0) or permission of the instructor.
For non-BHSc students
May not be taken with or after MICR 360/3.0
*May not be taken for credit towards the Plan requirements of the LISC Specialization or Major Plans.
After completing MICR 270, students will be able to define and illustrate:
- Organization of human immune system and how it functions.
- The unique features of the human defense mechanisms against microbial agents.
- The beneficial and detrimental interactions of the innate and adaptive branches of the human immune system.
- How the knowledge gained through this course can be translated to development of novel vaccines.
Assessment 1 – Module Quizzes (10%)
Upon completion of each of the five modules, students will have the opportunity to take a short quiz based on the main topics in the module. This quiz will be multiple choice questions and are designed to test the student’s knowledge and understanding of the material presented in the module. Each of the five quizzes is worth 2%, for a total of 10% of the final grade.
Assessment 2 – Module Discussion Question (15%)
Students will be divided into small tutorial groups and are required to answer the discussion question provided within each module. The student must provide support for their answer, using module content and, when applicable, outside sources. The student is also required to respond to a minimum of one of their peer’s posts, either challenging or supporting their ideas.
Assessment 3 – Journal Article Assignment (25%)
Students will be divided into groups of five. Throughout each module, one student (termed the seminar leader) is required to select one of the provided academic articles. The seminar leader must provide a one-page original summary of the article for their peers ahead of their narrated PowerPoint presentation which outlines the most important aspects of the article and relates it to module content.
Non-presenting students are required to participate in all of their peer’s seminars. The students must read the summary provided by the seminar leader and engage in an academic discussion following the presentation.
Assessment 4 – Scientific Poster (15%)
Students will be placed into groups of 4 or 5. Each group will be assigned a disease and must create a scientific poster. Students are required to perform external research and convey an understanding of the body’s immune response in fighting the disease.
Assessment 5 – Final Exam (35%)
Students are required to write a final proctored exam. The exam will consist of well-developed multiple choice questions. Students will have three hours to write it.
9–10 hours a week (108–120 hours per term).
Textbooks and Materials
- MICR 270 course notes via modules posted online.
- Relevant primary literature and review articles will be provided by the instructor pertaining to specific modules.
- Owen, J., Punt, J., & S. Stranford. (2012). Kuby Immunology, Seventh Edition. New York: W.H. Freeman and Company.