BMED 381, Clinical and Diagnostic Chemistry, covers a branch of laboratory medicine and explores the role of the laboratory in the diagnosis of disease. It describes molecules and macromolecules of biological importance and explains different chemical processes and metabolic pathways in the human body. The course focuses on interpretation of clinical and laboratory data with respect to diagnosis of different diseases.
Minimum 3rd year (Level 3) standing and one of (BCHM 270/3.0 OR BCHM 218/3.0), or permission of the instructor.
After completing BMED 381, students will be able to:
- Know biochemical structures of organic substrates inside the body to apply it to the evaluation, diagnosis, and interpretation of disease.
- Know the metabolic pathways of these biochemical molecules to use this information in determining the functions of different organs in the body.
- Know different organ function and use the laboratory to diagnose abnormalities or organ disorders.
All assessments will be graded using marking rubrics.
Assessment 1 – Group Case Study (20%)
Working in small groups, students will be assigned a case study for an unknown disease. Based on knowledge of the signs and symptoms of the disease and an understanding of the physiological disturbances that these symptoms may reflect, students will be responsible for proposing an appropriate battery of clinical diagnostic tools to evaluate and diagnose the disease. Students will present their case study for discussion. Evaluation will be based on TA and/or instructor as well as peer assessment.
Assessment 2 – Written Group Assignment (20%)
Working in small groups, students will be assigned unique diseases and will be responsible for developing a written report and accompanying presentation. This assignment will require students to educate their peers on the chemical and metabolic processes affected by their assigned disease, and how clinical and diagnostic chemistry is used to evaluate and diagnose that disease. Evaluation will be based on TA and/or instructor as well as peer assessment.
Assessment 3 – Quizzes (x3) (30%)
Upon the completion of each module (a total of three), students will be write short quizzes, ensuring comprehension of the material covered in each module. These questions will consist of short or long answer questions, focusing on integration of material as opposed to strict memorization. Each test will be worth 10%.
Assessment 4 – Final Examination (30%)
The final exam will include well-designed, case-based multiple choice questions and short answer questions that will test the students’ overall understanding and application of the course material, rather than rote memorization.
Tutorials will be held at the end of each learning section. TAs and/or the instructor will be available for designated hours to answer questions on the major concepts covered.
9–10 hours a week (108–120 hours per term).
Textbooks and Materials
BMED 381 course notes via modules posted online